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Help in a crisis


If there is an immediate danger to life, please dial 999 or go to your nearest Accident and Emergency Department.

I am in Gloucestershire

If you or someone you know needs help in a mental health crisis, call our crisis teams.

Call 0800 169 0398.

And choose one of the following options depending on your location:

  • Option 1 for Stroud and Cotswolds
  • Option 2 for Gloucester and Forest
  • Option 3 for Cheltenham, Tewkesbury and North Cotswolds

Please note: telephone calls may be recorded. If you do not want that to happen, please tell the person who answers your call and they will phone you back on a ‘non-recordable’ telephone.

The number is available 24 hours a day, 7 days a week. Occasionally, callers may be asked to leave their name and number on an answerphone. In these circumstances, staff will return the call within one hour.

I am in Herefordshire

If you are in Herefordshire and need support, please call us using one of the following numbers:

  • Monday to Friday, 9am – 5pm, please contact the team or service who currently provide your care.
  • Monday to Friday, 5pm – 9am and 24 hours on weekends and bank holidays, please call our Mental Health Matters Helpline on: 0800 015 7271

These contact numbers are for people already in contact with our services. If you are not currently in contact with us, please call 111 or your GP.

Our out of hours, weekend and bank holiday service is provided by Mental Health Matters.

If you need help but are not in crisis, please contact your GP if in opening hours, or 111. If you don’t have a GP use the NHS service search to locate the nearest one to you. If your query is not urgent, you can find our contact details here.

Are you feeling vulnerable? Do you need to talk to somebody now?


Call free on 116 123
If you are experiencing feelings of distress or despair, including those which could lead to suicide, you can call the Samaritans.

Stay Alive App

A pocket suicide prevention resource for the UK, packed full of useful information and tools to help you stay safe in crisis. You can use it if you are having thoughts of suicide or if you are concerned about someone else who may be considering suicide. The app can be accessed through the Apple Store, Google Play and downloaded as a pdf.


Call free on 0800 11 11
If you are a child or a young person you may want to speak to Childline.


Call 0808 816 0606
Or text 07537 410 022
A safe, supportive, non-judgmental and informative service for people who self harm, their friends, families and carers.
Opem every day 5pm – 10pm for phone and text support.


The Research Team

The trust research team is a dedicated group of nurses and clinical studies officers who promote research within the trust.

The research team is funded by the National Institute for Health Research (NIHR). This group works with educational providers, hospitals and commercial companies to promote research studies. Two of our senior research nurses are funded by Cobalt. This enables us to run commercial research projects.

Our Policy

Our Trust is research-focused. We look for opportunities to promote research and development and are willing to provide the necessary training for our staff to be involved in research.

Whilst we have our dedicated research team, we require all of our staff to be proactive in promoting research so that the maximum number of our patients have the opportunity to take part in research studies.

All research carried out by the research team is only undertaken once a study is approved by the IRAS (Integrated Research Application System) and the HRA (Health Research Authority).

Patient safety is at the forefront of our choices when deciding if we will undertake a research study, and therefore we have strict standard operating procedures (SOP), to ensure that our patients are adequately cared for. All research staff including non-clinical have undergone medical emergency response training.

We will endeavor to undertake studies that include not just our patients, but also their families and carers, to better understand the needs of families, as well as the patients.

Studies currently recruiting participants

If you are interested in taking part in any of our studies, or would like to find out more, contact the research team.

Telephone: 01242 634490
Email: 2gnft.research@nhs.net

Dementia studies


This is a study that looks at what it means to live with dementia. The aim of the study is to learn what helps people to live well with dementia.

Participant eligibility

  • Aged under 65 or over 90 with a diagnosis of dementia
  • Be any age with a diagnosis of frontotemporal dementia, dementia with Lewy bodies or Parkinson’s disease dementia
  • Have the capacity to give informed consent
  • Have a relative or friend who is able to act as a study partner

Participant requirements

Candidates will be required to have an interview and memory test with one of the research team.


This research study aims to reduce symptoms of agitation and frustration sometimes experienced by those with dementia. The aim of the study is to try and improve the treatment and care of people living with dementia.

Participant eligibility

  • Have a diagnosis of probable or possible Alzheimer’s disease or mixed dementia
  • Have evidence that agitated behaviours have not responded to management by other treatment options
  • Ability to provide written informed consent or consultee provide written informed consent
  • Have an available consenting carer (paid or unpaid).

Participant requirements

  • Complete a consent form
  • Complete a 12 week course of trial tablet or placebo tablet
  • Provide two blood tests and two ECGs during the course of the 12 weeks
  • Complete a short questionnaire and memory test three times during the 12 weeks
  • Carer will need to complete three questionnaires and have three telephone discussions.
DLB - Dementia Lewy Bodies

This is a research study following on from AD Genetics. Our current research into Alzheimers disease has been successful in finding many previously unknown genes that are involved in Alzheimer’s disease. 

The DLB study aim is to use the expertise developed from studying Alzheimer’s disease to better understand the biological and genetic influences behind dementia with Lewy bodies.

Participant Eligibility

  • Diagnosed with Dementia Lewy bodies
  • Capacity to provide informed consent or available consultee/representative

Participant Requirements

  • Provide a blood or saliva sample for genetic analysis
  • White European ethnicity
  • Have a study partner

Free-Cog is a research study looking at an assessment tool that will be used by clinicians to assess cogantive and functional abilities. The aim is to compare a new test with those currently in use.

Participant Eligability

  • Aged 18 or over
  • Have been referred to the memory service for a memory assessment or has a diagnosis of dementia/memory impairment.

This study also is looking for healthy controls

  • Aged 18 or over
  • No diagnosis of dementia or memory impairment
  • Has no concerns of memory impairment

Participant Requirements

  • Complete a consent form
  • Complete the Free-Cog assessment prior to completion of standard memory assessment.
Alzheimer's Disease Genetics

The purpose of the Alzheimer’s Disease Genetics (AD Genetics) study is to help identify the genes that may be responsible for causing Alzheimer’s disease.

With your help, we can learn more about why people develop Alzheimer’s disease, which we hope will result in into new methods of diagnosis and better treatments for future generations.

Who can get involved?

  • The patient must have a diagnosis of Alzheimer’s
  • The onset of Alzheimer’s symptoms must have occurred before 70 years of age.
  • The patient must be of White ethnicity.

What do participants need to do?

We will arrange a suitable time to meet with you to complete the following:

  • Sign a consent form.
  • Provide a blood sample.
  • Complete an interview in person, which will take between 1 ½ to 2 hours.
Graduate 2

A trial to test the effect of an investigational treatment for people who may be in the early stages of Alzheimer’s disease.

The study will assess whether a drug, being developed by Roche Products Ltd, can help prevent or slow down the symptoms of memory loss or Alzheimer’s disease.

Who can get involved?

  • Participants must be aged 50-90 with mild Alzheimer’s disease or MCI.
  • Participants must have a friend or relative who knows them well and can act as a study partner. This will include attending clinic visits when necessary and answering questions on symptoms and how the participant is coping day-to-day.

What do participants need to do?

Following completion of a consent form and initial screening assessments, participants will be required to take a trial medication or placebo for 100 weeks by a 2/4 weekly injection in the tummy area.

MRI, ECG scans, blood and memory tests will be carried out along with quality of life assessments.

Mental health studies

TACK: Tackling chronic depression

Using an app called DIALOG+, which aims to improve quality of life in patients with chronic low mood.

Who can get involved?

We recruit clinicians who have at least four patients on their caseload who meet our eligibility criteria, then approach potentially eligible patients.

Clinician eligibility criteria

  • Qualified mental health or healthcare professional (including band 4 support workers, social workers and occupational therapists)
  • Working in healthcare for at least six months
  • Have at least 4 patients with chronic low mood on their caseload, (or have the ability to ‘case swap’ with other team members) and see these patients regularly (e.g. once a month)
  • No plans to leave their post within the next six months

Patient eligibility criteria

  • Between 18 and 80 years old
  • Clinical expression of non-psychotic low mood with a duration of at least 2 years (can be co-morbid with other conditions such as anxiety, personality disorder, etc.)
  • No primary substance misuse diagnosis or organic mental disorder (i.e. F00-F19)
  • Capacity to provide informed consent
  • Ability to speak and understand English

What do participants need to do?

  • Clinicians will be randomized to either the control group (delivering standard care) or intervention group (delivering the solution-focused, app-based intervention alongside standard care).
  • Clinicians in the intervention group will receive a 90 minute training session in delivering the intervention. At the end of the trial, clinicians in the control group will be offered this CPD opportunity. All clinicians taking part will receive an iPad to use during the study, which they are free to keep afterwards.
  • Participants will continue their regular sessions with their clinicians either as standard or with the addition of DIALOG+
  • At four intervals, patients will be asked questionnaires about their quality of life, mood, and care and will receive cash or vouchers as a thank you from the central research team at NELFT

Exploring the cause and prevalence of memory problems in people with mental health, neuro-developmental and neuro-degenerative disorders.

Who can get involved?

  • Anyone, whether or not they have a diagnosis of a mental health condition or dementia.
  • Age over 16 years.
  • Fluent in English language.

What do participants need to do?

The participants will be asked to complete a questionnaire which will take approximately 15-20 minutes.


PPiP-2 is the follow up study for PPiP. The first phase (PPiP) was looking at the presence of antibodies in patients with first episode psychosis. This pilot study provided the first systematic evidence that some cases of schizophrenia may have an immune mediated disorder.  PPiP-2 aims to look at its prevalence in patients with a more general diagnosis of psychosis.

Who can get involved?

Participants must be aged 18-70 with acute psychosis symptoms lasting for at least the past two weeks but no longer than two years, and not a primary drug induced psychosis.

What do participants need to do? We will arrange a suitable time to meet with you and complete the following:

  • Sign a consent form
  • Provide a blood sample
  • Ask a few short questions, lasting approx. 15 minutes.
Bipolar Disorder Research Network (BDRN): Molecular Genetics

A genetic study looking into how genes and external factors (like stressful life events) interact with each other to make people more likely to develop bipolar disorder than others.

Who can get involved?

Participants must:

  • Have had a Bipolar diagnosis with at least one episode of mania/hypomania at any time in the past (including: bipolar I disorder, bipolar II disorder, bipolar disorder not otherwise specified, post-partum psychosis or schizoaffective disorder)
  • Be over 18
  • Speak and understand English fluently
  • Be able to provide written consent

What do participants need to do?

  • An interview in your own home or over the telephone to ask about your experiences and the kind of symptoms you’ve had in the past.
  • Complete some questionnaires.
  • Potentially give a small blood sample: this is for the genetic aspect of the investigation.

Study examining what leads to the development of mental health problems, from genetics and biology to psychological and environmental factors.

Who can get involved?

Participants with a diagnosis of:

  • Bipolar affective disorder (type 1/type2/NOS)
  • Schizophrenia
  • Schizoaffective (bipolar/depressed types)
  • Psychosis (including post-natal psychosis)
  • PTSD
  • A learning disability

What do participants need to do?

  • A blood test
  • A short questionnaire

A randomised controlled trial of an online intervention for carers who are supporting someone affected by psychosis. Who can get involved?

  • You need to be a carer of a person affected by psychosis
  • You need to have at least weekly contact with the person you care for although these contacts do not have to be face to face
  • You need to be living in England
  • You need daily access to the internet
  • You must be over 18.

What do participants need to do?

  • The study consists of a 20 week intervention where you will need to spend about one hour per week using an online platform. This will be alongside any other care.
  • People who are randomised into control and usual care will still receive the intervention after 20 weeks.
Power Up

Are you a parent/caregiver of a child accessing CAMHS?

Would you like to help develop an app to support shared decision making in CAMHS?

Power Up is a mobile app being designed to help parents become more involved in making decisions about their child’s care and treatment. Stage 1 of this study, involves a 1 hour interview OR 2 hour focus group attendance and Stage 2 involves using the app and answering baseline and follow up questionnaires. You can choose to participate in 1 OR both stages of this research.

For further information on this study and how you can participate, please contact Shaun Liverpool on 0203 1089888 or email: shaun.liverpool@annafreud.org

We will cover all travel costs relating to your participation.

Learning disabilities studies

Adult Autism Cohort
Very little research has been undertaken into the life experiences of adults and older people on the autism spectrum. The aim of this study is to collect information from adults on the autism spectrum and their relatives, and update the information from time to time to see how people’s lives change.

Who can get involved?

  • adults on the autism spectrum of all ages and abilities
  • relatives are able to join and give information about themselves and their own lives
  • some relatives or carers can respond for people with an autism spectrum condition who cannot take part themselves

What do participants need to do?

  • Complete questionnaires at various time points either online or by post.

Our partners

National Institute of Health Research (NIHR)

NIHR is funded by the Department of Health to improve the health and wealth of the nation through research. They ensure that the NHS is able to support the research of other funders to encourage broader investment in, and economic growth from, health research.

They work with charities and the life sciences industry to help patients gain earlier access to breakthrough treatments. They also train and develop researchers to keep the nation at the forefront of international research.

Cobalt Health

Cobalt is a diagnostic imaging centre. They provide MRI and PET scans for our clinical trials.

Research4Gloucestershire (R4G)

Research4Gloucestershire is a collaboration between

  • Gloucestershire Health and Care NHS Foundation Trust
  • Gloucestershire CCG, Gloucestershire County Council
  • Gloucestershire Hospitals NHS Foundation Trust
  • University of Gloucestershire
  • Cobalt Health.

Our Regulator

The Health Research Authority is an executive non-departmental public body (NDPB), sponsored by the Department of Health and Social Care. 

They are one of a number of organisations that work together in the UK to regulate different aspects of health and social care research. Their core purpose is to protect and promote the interests of patients and the public in health and social care research. 

 In order to achieve this they:

Locations for this service